By its very nature JPEG compression is a lossy process. According to the site resizer.app: "The quality of a JPEG image decreases as its file size decreases, and constantly editing and re-saving JPEG photos may further cause the quality to degrade."
To me, the real question is whether I or the person using the JPEG will notice the loss of quality. If it is noticeable, using the RAW format of the image for editing is recommended.
On a Mac since 1984.
Currently: 24" M1 iMac, M2 Pro Mac mini with 27" BenQ monitor, M2 Macbook Air, MacOS 14.x; iPhones, iPods (yes, still) and iPads.
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