I used to rely on www.macupdate.com for obtaining updates, but once I had some issues with the MacUpdate Installer, I stopped getting updates that way. I instead go to the site for the product, and download updates from there. (Some software, of course, have the "Check for Updates" feature, and that can be used to get updates directly from the company's site).

Also, MacUpdate is not always up to date with information. For example, the new version of EtreCheck, which came out last week, was finally listed yesterday on MacUpdate. Also, they are definitely behind with updates for Office 2011. Right now, MacUpdate shows version 14.5.8 being available, but version 14.6.0 has been out for at least 2 weeks!

Another example si 1Password. The update for it came out on Monday, but it did not show up on MacUpdate until Tuesday. True, only a 1 day delay, but as I stated, it is worse for a number of other products.