In addition to the above, if you have access to another mouse, one that would not require USB Overdrive, give that a try for a day or two and see if the problem pops up.
On a Mac since 1984. Currently: 24" M1 iMac, M2 Pro Mac mini with 27" BenQ monitor, M2 Macbook Air, MacOS 14.x; iPhones, iPods (yes, still) and iPads.
