The only caveat about CS 5 is that it requires Java 6, which is absent from Yosemite. That's the bad news. The good news is that you will be prompted, after installing Yosemite, to download and install Java 6. That's what happened to me and Photoshop CS 5 works fine. As to MS Office, I don't have Office 2011 but Office 2008 works well. As Freelance said, Office 2011 is OK also, as I would have expected since the previous version works as well.
Jon
macOS 11.7.10, iMac Retina 5K 27-inch, late 2014, 3.5 GHz Intel Core i5, 1 TB fusion drive, 16 GB RAM, Epson SureColor P600, Photoshop CC, Lightroom CC, MS Office 365
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