Check
these links for ways to uninstall MacKeeper.
There are several ways to optimize a Mac. One (free) way is to run the default tasks in the Automation tab of
OnyX 2.4.0. If you opt to repair permissions (and you can uncheck that box), this may take a long time. Probably, repairing permissions is unnecessary.
You can also boot from the Install Disk and run Disk Utility to Repair Disk, but if I recall from another thread, you already did this. If you want a heavy-duty utility (not free), you can rebuild the directory with
Disk Warrior, a venerable app that can often repair things that stump Disk Utility.