The one potential gotcha is that OTA wireless updates are usually delta updates (you transfer only the parts of iOS that have changed), whereas wired updates are full fat updates (they contain a full install of the entire OS), and so wired updates are bigger.
That won't be the case with iOS 7, where the whole operating system is going to be updated regardless. But I remember when iOS 6.1.3 was released, the OTA update was tiny, and the wired update was huge.
