...the whole idea raises the same question as licking toads to get high. What would have possessed anyone to try it in the first place?
I can't imagine anybody trying to get high by licking a toad; the effect was probably the accidental discovery of some love-struck princess who thought that a big, sloppy kiss would get her a prince.
On the other hand, though:
From Wikipedia, the free encyclopedia
Psychoactive toad is a name used for toads from which psychoactive substances from the family of bufotoxins can be derived. The skin and poison of Bufo alvarius (Colorado River toad or Sonoran Desert toad) contain 5-MeO-DMT and bufotenin. Other species contain only bufotenin. 5-MeO-DMT and bufotenin both belong to the family of hallucinogenic tryptamines. Due to these substances the skin or poison of the toads may produce psychoactive effects when ingested.