In another thread Tacit mentioned radical longevity and, while this may/may not be part of that idea, the Mayo Clinic has done some interesting genetic engineering with
senescent cells. They haven't concluded that flushing these cells actually extends a lifetime but it sure seems it would make aging a lot more comfortable.
I have to admit feeling a bit sorry for the mice. Apparently they have specially designed mice who age rapidly, to allow for testing that represents a lifetime, and it doesn't matter how well a mouse tales care of himself - he's going to drop from a heart attack.