....but a second bootable volume on either the internal or external drive is sufficient to avoid cloning a booted volume.
I was wondering the same thing as Alex. (Everyone in class is always so happy when some other kid is willing to raise his arm first) So, to be clear, this is what I now understand.
I would repartition my backup drive into two volumes. In one partition I install a system and Super Duper. The other partition would be reserved for my Clone.
When I make my clone I reboot from the drive that has the system and Super Duper, and I instruct SD to make a clone of my main drive onto the partition reserved for it.
N'est-ce pas? (My Time Machine is on a separate drive)