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Have you tried deleting the printer driver, restarting your computer, and then re-installing the printer? That should very effectively flush all the print queues and cache files in case there is some conflict there.Bingo!
Thanks for the suggestion; it never occurred to me to delete my printer (which I was only keeping around for nostalgic reasons, anyhow, since there are no 10.6 drivers for it).
I deleted and restarted, and Excel now responds to command-P as expected.
Is it unusual to run into an issue like this with only one app out of many?
Thanks, again.