You probably can remove them. If you want to be extra cautious, put them in the trash but don't empty the trash. If everything works well (give yourself some time to find out), then empty the trash. Alternatively, copy them to another medium (CD, DVD, whatever) and then trash them from your hard drive. If necessary, you can restore them.

Jon

macOS 11.7.10, iMac Retina 5K 27-inch, late 2014, 3.5 GHz Intel Core i5, 1 TB fusion drive, 16 GB RAM, Epson SureColor P600, Photoshop CC, Lightroom CC, MS Office 365