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#48006 - 02/16/18 10:43 AM Failure = Success
grelber Offline


Registered: 08/05/09
Loc: North of 49th ||
I love this Console message (which pops up all the time)!

2018-02-16 1:37:01.871 pppd: publish_entry SCDSet() failed: Success!

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#48007 - 02/17/18 09:01 AM Re: Failure = Success [Re: grelber]
Ira L Offline


Registered: 08/13/09
Loc: California
Many studies are a success when they fail. Data analyses are filled with these kinds of results. For example, the drug under examination failed to be statistically significantly different from the placebo in observed side effects. That failure is a success for the manufacturer of the drug.

Even so, it is contrary to our normal perceptions and experiences—failures in school are generally not a good thing—to associate success with failure. smirk
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#48009 - 02/18/18 04:17 PM Re: Failure = Success [Re: Ira L]
grelber Offline


Registered: 08/05/09
Loc: North of 49th ||
'Tis true. It all depends on how one asks the question. Of course, in the example given, it would be an excellent outcome if the effects of the drug were significantly better than a placebo ... but that wasn't what was asked (or answered).

Continuing with this particular example type, let's look at the 2 main shingles (herpes zoster) vaccines now on the market.
Zostavax (Merck & Co) came on the scene about 10 years ago. It had fair immunogenicity which tended to wane the older the recipients were. Its adverse side effects were nominal.
More recently, Shingrix (GSK) has been praised for being considerably more efficacious and seems to have far greater immunogenicity in all age groups. Its adverse side effects on the other hand are more numerous and arguably more serious than those of Zostavax; interestingly, they are reported [in the product monograph] to be far more frequent and nasty in the 50-69 year range than in the 70+ cohort. [Finally, we septua- and octogenarians can thumb our noses at our juniors. grin ]

Success vs failure is a 'movable (~ mutable) feast'.

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#48010 - 02/18/18 05:55 PM Re: Failure = Success [Re: grelber]
artie505 Online


Registered: 08/04/09
So we see the flip side of the coin as respects the vaccines, i.e. success = failure.
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In Memory Of Harv: Those who can make you believe absurdities can make you commit atrocities. ~Voltaire

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