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I have installed a Drobo S to backup my Mac Mini using FW 800. The initial BU took quite awhile and finished with no errors. The following incremental BU's all finished with and error message to try again. I retrieved the messages from console. Any help deciphering this would be much appreciated

5/12/12 4:30:15.369 PM com.apple.backupd: Starting standard backup
5/12/12 4:30:15.396 PM com.apple.backupd: Backing up to: /Volumes/Drobo Backup/Backups.backupdb
5/12/12 4:30:15.579 PM com.apple.backupd: 2.16 TB required (including padding), 15.01 TB available
5/12/12 4:30:15.581 PM com.apple.backupd: Waiting for index to be ready (101)
5/12/12 4:30:18.200 PM com.apple.backupd: Copied 29 files (2.9 MB) from volume Movies 1.5TB.
5/12/12 4:30:18.422 PM com.apple.backupd: Error: (2) setxattr for key:com.apple.backupd.SnapshotVolumeUUID path:/Volumes/Drobo Backup/Backups.backupdb/James Tomkins’s Mac mini/2012-05-11-162102.inProgress/51ECBDA3-8A43-428A-B196-411F7991EC97/iTunes/Music 1TB size:37
5/12/12 4:30:18.422 PM com.apple.backupd: Stopping backup.
5/12/12 4:30:18.426 PM com.apple.backupd: Copied 29 files (2.9 MB) from volume iTunes/Music 1TB.
5/12/12 4:30:18.426 PM com.apple.backupd: Copy stage failed with error:11
5/12/12 4:30:28.450 PM com.apple.backupd: Backup failed with error: 11

There are known issues with Drobo drives and Time Machine. Time Machine tends to fail unless you back up to a disk image on a Drobo. You might find these instructions helpful if you are using Lion. For Snow Leopard, follow these instructions.

Drobo is reportedly working on a firmware fix for the Drobo S for Time Machine.